Penelitian Noni Hingga Tahun 1990

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Planta Medica 56(5):430-434 (1990)
Analgesic and Behavioral Effects of Morinda citrifolia
Chafique Younos, Alain Rolland, Jacques Fleurentin, Marie-Claire Lahners, Rene' Misslin, and Francois Mortier

Editor's note: this was a study of the roots of Morinda citrifolia.) The traditional therapeutic indications for the use of Morinda citrifolia L. (Rubiaceae) have been investigated. The lyophilised aqueous extract of roots of M. citrifolia was evaluated for analgesic and behavioural effects in mice. The extract did not exhibit any toxic effects but did show a significant, dose-related, central analgesic activity in the writhing and hotplate tests; this effect was confirmed by the antagonistic action of naloxone. Furthermore, administration of M. citrifolia extract at high dosages decreased all behavioural parameters in the two compartment test, the light/dark choice situation test, and the staircase test; together with the induced sleeping time, these results are suggestive of sedative properties.

Science in New Guinea 14(1): I7 (1988)
Antibacterial Activity of Some Medicinal Plants of Papua New Guinea
A.J. Leach, D.N. Leach, and G.J. Leach

Ten species of plants used by the people of Papua New Guinea to treat external bacterial infections was assessed. Activity was seen in extracts of Morinda citrifolia. The widespread medicinal use of these plants would suggest they do contain pharmacologically active substances.

Journal of the Chemical Society, Pakistan. VOL. 2, NO.2 (1980) Phytochemical Report
Isolation of β-Sitosterol and Ursolic Acid from Morinda Citrifolia Linn.
Viqar Uddin Ahmad and Shaheen Bano

A crystalline greenish yellow solid was extracted from the fresh leaves of Morinda citrifolia Linn. On recrystallization from methanol, white, shiny crystals were obtained. This compound was identified as ursolic acid. A second substance isolated was β-sitosterol.

Planta Medica, 1979, 36(2): 186-187
Some Chemical Constituents of Morinda citrifolia
Oscar Levand and Harold O. Larson

This paper outlines the process of separating several compounds from dried fruit of Morinda citrifolia L. (asperuloside, glucose, caproic and caprylic acids).

Antiseptic 67(3): 167-71 (1970)
Preliminary Phytochemical and Pharmacological Study of Morinda citrifolia, Linn.
N. Krisha Moorthy and G. Shama Reddy

The total extract of the roots of Morinda citrifolia, Linn. were used as an effective hypotensive agent in a majority of patients treated by Dang Van Ho in 1955. A preliminary report on the phytochemical and pharmacological effects of Morinda citrifolia roots and leaves is presented. Extraction procedures to isolate anthraquinones from the roots are given.

Pacific Science 4: 167-183 (1950)
The Antibacterial Properties of Some Plants Found in Hawaii
O.A. Bushnell, Mitsuno Fukuda, and Takashi Makinodan

Extracts from 17 plants were tested on 5 strains of pathogenic enteric bacilli. Morinda citrifolia was effective against the intestinal pathogens (Ps. aeruginosa, M. pyogenes and E. coli). The extract from the ripe Morinda citrifolia fruit was shown to have moderate antibacterial properties against Salmonella typhosa, Salmonella montevideo, Salmonella schottmuelleri, Shigella paradys, BH and Shigella paradys.

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